Rare Eye Complication in Paclitaxel Users — A Warning for Early Diagnosis

What Breast Cancer Patients Need to Know:

A new study shows that Paclitaxel, a drug used for the treatment of breast cancer, can, in very rare cases, cause a serious complication known as Central Retinal Artery Occlusion (CRAO). In this condition, blood flow to the retina becomes obstructed, potentially leading to sudden vision loss.

Dr. Harsh Jain and his research team warn that physicians and patients should be aware of this complication and seek prompt ophthalmologic evaluation if any ocular symptoms — such as sudden blurred vision — occur. While rare, CRAO is considered an ocular emergency requiring immediate treatment.

Paclitaxel has previously been recognized for its neurological and hypersensitivity side effects, but this study also highlights its association with Central Retinal Artery Occlusion. The researchers emphasize that, although the likelihood of this complication is extremely low and should not lead to discontinuation of the drug without consulting a physician, awareness is essential for early diagnosis and prevention of severe damage.